Helicobacter pylori babA2 Positivity Predicts Risk of Gastric Cancer in Ardabil, a Very High-Risk Area in Iran
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چکیده
منابع مشابه
Helicobacter pylori babA2 Positivity Predicts Risk of Gastric Cancer in Ardabil, a Very High-Risk Area in Iran.
BACKGROUND Ardabil, a Northwestern province of Iran, was found to have the highest rate of gastric cancer (GC) in the country (ASRs = 51.8/100,000 for males and 24.9/100,000 for females) and one of the highest gastric cardia cancer rates in the world. The aim of the present study was to assess the associations of the cagA and babA2 status of Helicobacter pylori with GC in the Ardabil population...
متن کاملHelicobacter pylori vacA d1 genotype predicts risk of gastric adenocarcinoma and peptic ulcers in northwestern Iran.
BACKGROUND There is a close relationship between Helicobacter pylori (H pylori)-specific factors and different gastroduodenal diseases. The present study aimed to investigate the prevalence of vacA d1, d2 genotypes in the H pylori isolates from patients with gastric adenocarcinoma, peptic ulcer disease (PUD) and gastritis in East Azerbaijan region, where the incidence of gastric cancer (GC) is ...
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Gastric cancer is a leading cause of cancer-related death worldwide. Helicobacter pylori infection is the strongest known risk factor for this malignancy. An important goal is to identify H. pylori-infected persons at high risk for gastric cancer, so that these individuals can be targeted for therapeutic intervention. H. pylori exhibits a high level of intraspecies genetic diversity, and over t...
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background: gastric cancer (gc) is the fifth common malignant disease and the third leading cause of cancer-related mortality in the world. ardabil, a northwestern province of iran, includes the highest rate of gc within the country. helicobacter pylori (h. pylori) vaca gene plays a major role in generating and maintaining the gastric inflammatory response , which alters the enteric nervous sys...
متن کاملRisk of gastric cancer in children with Helicobacter pylori infection.
BACKGROUND Helicobacter pylori (H. pylori) is the most common chronic infectious agent in the stomach. Most importantly, it may lead to atrophy, metaplasia and cancer. The aim of this study was to investigate the incidence of H. pylori infection and to detect early mucosal changes that may lead to malignant degeneration in children. MATERIALS AND METHODS Children who underwent upper gastroint...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Cancer Prevention
سال: 2016
ISSN: 1513-7368
DOI: 10.7314/apjcp.2016.17.2.733